smAP: Manipulating DNA by Ultrasound - Single-Molecules Go Acoustic
نویسندگان
چکیده
منابع مشابه
Manipulating the Acoustic Wave by Acoustic Metamaterials
Our research efforts concentrate on focusing photon and sound into sub-wavelength scales. While we emphasize on new insights of material and device design from fundamental approaches, we also actively pursue the applications of our technology in the areas of nanofabrication, energy conversion, communication, and biomedical imaging. Acoustic metamaterials promise new applications for steering an...
متن کاملAcoustic Forest for SMAP-Based Speaker Verification
In speaker verification, structural maximum-a-posteriori (SMAP) adaptation for Gaussian mixture model (GMM) has been proven effective, especially when the speech segment is very short. In SMAP adaptation, an acoustic tree of Gaussian components is constructed to represent the hierarchical acoustic space. Until now, however, there has been no clear way to automatically find the optimal tree stru...
متن کاملWafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules
Wafer-scale fabrication of complex nanofluidic systems with integrated electronics is essential to realizing ubiquitous, compact, reliable, high-sensitivity and low-cost biomolecular sensors. Here we report a scalable fabrication strategy capable of producing nanofluidic chips with complex designs and down to single-digit nanometre dimensions over 200 mm wafer scale. Compatible with semiconduct...
متن کاملPiezoresistivity in single DNA molecules
Piezoresistivity is a fundamental property of materials that has found many device applications. Here we report piezoresistivity in double helical DNA molecules. By studying the dependence of molecular conductance and piezoresistivity of single DNA molecules with different sequences and lengths, and performing molecular orbital calculations, we show that the piezoresistivity of DNA is caused by...
متن کاملSequencing single molecules of DNA.
In 2004, the NIH set a remarkable challenge: the 1000 dollars genome. Roughly speaking, success would provide, by 2015, the ability to sequence the complete genome of an individual human, quickly and at an accessible price. An intermediate goal of a 100,000 dollars genome was set for 2010. While the cost of Sanger sequencing has dropped dramatically over the past two decades, it is unlikely tha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2014
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.11.2190